Many of the gene products of completely sequenced organisms are "hypothetical"
,they cannot be related to any previously characterized proteins,
and so are of unknown structure and function.
Structure 2 Function (S2F) is a structural genomics projects that aims to solve
structures of these poorly characterized proteins by using
X-ray crystallography and protein NMR techniques. The initial set of targets was
selected from the first completly sequenced bacterial genome of the